Classification of particles, part one
- The granules are classified according to the date of release of the active substances present in them into the body and the start of the vital processes (absorption, metabolism, elimination).
- This all differs according to the methods of taking the granules, such as a dissolved medicine, a capsule, or an envelope to be released into the intestines...etc
Effervescent granules:
- They are granules formed from powders in a specific way that are stored in certain places away from moisture and heat to maintain their effectiveness.
- It is dissolved outside the mouth with an appropriate amount of water and interacts by producing bubbles containing carbon dioxide. At the moment of mixing the granules with water, these bubbles begin to come out, like Voltfast?
- A chemical reaction takes place between the granules and the water, an acid and a base reaction such as sodium carbonate and any strong acid that leads to the production of free gases of carbon dioxide in large quantities until all the materials that are stored in a place away from moisture and heat react .
- Because water is a strong catalyst for reaction, great care must be taken while storing the granules, because if the granules are exposed to this stimulus in small quantities, the reaction will occur until all the water that reaches these granules is consumed.
If the granules interact with water, can it be stopped?
- The granules can be stored according to each type and method of swallowing the drug. It was a liquid that has a validity period, and if it was a capsule, it has a period that differs from the suspensions, and it has a period that differs from if it was external or internal use.
- These granules lie in storage for a longer period of time than powders, as long as they are exposed to bad weather conditions, humidity and heat.
Storing granules in the long term is better than storing powders?
- Because the granules have fewer points of contact with each other than powders when they are connected to more than one segment with other adjacent particles, we conclude from here that it will have less cohesion and adhesion than powder.
- It is possible to shake the granules to return them to their original state, while the powder settles slowly, so it takes places between itself to fully adhere to more points, and it becomes a cake mold!